吴官维 特聘研究员

吴官维，特聘研究员，博士，植物病理学专业。农产品质量安全全国重点实验室固定研究人员，生物学博士和硕士研究生导师。本科（2005.9-2009.6）和博士（2009.9-2014.6）均毕业于华中农业大学植物科学技术学院。于2015.7至2019.3在加拿大农业部伦敦研究和发展中心Aiming Wang教授实验室开展博士后研究。

本人研究方向为以马铃薯Y病毒属病毒重要成员芜菁花叶病毒（turnip mosaic virus, TuMV）为模式，系统研究三个核心问题：病毒如何在细胞内完成复制？植物如何识别并反击？病毒又如何再次逃逸？

近5年以第一/通讯（含共同）在Plant Biotechnology Journal、New Phytologist和PLoS Pathogens等期刊发表高水平论文9篇，共同主编Methods in Molecular Biology系列英文专著1部。主持国家自然科学基金面上项目2项和省基金重点项目1项。担任BMC Plant Biology等期刊编委和PLoS Pathogens等期刊独立审稿人。

研究方向

植物病毒和植物间互作机制。

招生类型

学术型

招生级别

一级学科名称

二级学科/方向

博士和硕士

生物学

生化和分子生物学/植物病毒学

近5年主持的主要科研项目

1. 32370144，国家自然科学基金面上项目，芜菁花叶病毒蛋白酶NIa-Pro切割寄主Dbp5激活寄主免疫的分子机制，吴官维，主持，2024.1-2027.12。

2. 32070165，国家自然科学基金面上项目，液泡分选受体介导芜菁花叶病毒6K2转运促进病毒侵染的作用机制研究，吴官维，主持，2021.1-2024.12。

3. LZ24C140001，浙江省自然科学基金重点项目，受体激酶Feronia介导的芜菁花叶病毒VPg蛋白磷酸化的分子机制研究，吴官维，主持，2024.1-2026.12。

近5年代表论文和专著

#通讯作者，*第一作者

2025

1. Penghuan Rui; Zhaoxing Jia; Xinxin Fang; Tianqi Yu; Wenqi Mao; Jiajia Lin; Hongying Zheng; Yuwen Lu; Feng Yu; Jianping Chen#; Fei Yan#; Guanwei Wu#. A plant viral effector subverts FER-RALF1 module mediated intracellular immunity. Plant Biotechnology Journal, 2025, 23: 2734-2751.

2. Zhaoxing Jia; Penghuan Rui; Xinxin Fang; Kelei Han; Tianqi Yu; Yuwen Lu; Hongying Zheng; Jianping Chen#; Fei Yan#; Guanwei Wu#. Proteolysis of host DEAD-box RNA helicase by potyviral proteases activates plant immunity. New Phytologist, 2025, 245: 1655-1672.

2024

1. Xinxin Fang; Zhaoxing Jia; Tianqi Yu; Penghuan Rui; Hongying Zheng; Yuwen Lu; Jiejun Peng; Shaofei Rao; Jian Wu; Jianping Chen; Fei Yan#; Guanwei Wu#. FATTY ACID DESATURASE4 enhances plant RNA virus replication and undergoes host vacuolar ATPase-mediated degradation. Plant Physiology, 2024, 196: 1502-1517.

2. Guanwei Wu; Jianping Chen; Aiming Wang#; Fei Yan#. Unveiling the viroporin arsenal in plant viruses: Implications for the future, PLoS Pathogens, 2024, 20: e1012473.  

3. Guanwei Wu; Xinxin Fang; Tianqi Yu; Jianping Chen; Fei Yan#. Turnip mosaic virus pathogenesis and host resistance mechanisms in Brassica, Horticultural Plant Journal, 2024, 10: 947-960.

4. Guanwei Wu*; Liping Wang*; Rongrong He*; Xiaoyan Cui; Xin Chen; Aiming Wang#. Two plant membrane- shaping reticulon-like proteins play contrasting complex roles in turnip mosaic virus infection, Molecular Plant Pathology, 2024, 25: e70017.

2022

1. Guanwei Wu; Zhaoxing Jia; Kaida Ding; Hongying Zheng; Yuwen Lu; Lin Lin; Jiejun Peng; Shaofei Rao; Aiming Wang; Jianping Chen#; Fei Yan#. Turnip mosaic virus co-opts the vacuolar sorting receptor VSR4 to promote viral genome replication in plants by targeting viral replication vesicles to the endosome, PLoS Pathogens, 2022, 18: 0-e1010257.

2. Guanwei Wu; Zhaoxing Jia; Penghuan Rui; Hongying Zheng; Yuwen Lu; Lin Lin; Jiejun Peng; Shaofei Rao; Aiming Wang; Jianping Chen#; Fei Yan#. Acidic dileucine motifs in the cylindrical inclusion protein of turnip mosaic virus are crucial for endosomal targeting and viral replication, Molecular Plant Pathology, 2022, 23: 1381-1389.

2020

Guanwei Wu; Xiaoyan Cui; Zhaoji Dai; Rongrong He; Yinzi Li; Kangfu Yu; Mark Bernards; Xin Chen#; Aiming Wang#; A plant RNA virus hijacks endocytic proteins to establish its infection in plants, Plant Journal, 2020, 101: 384-400.

专著

Xiaofei Cheng and Guanwei Wu (eds.), 2024, Double-stranded RNA: Methods and Protocols, Methods in Molecular Biology 2771, Humana Press, New York, NY.

学术兼职

BMC Plant Biology, Manuscript editor, 2024-；

Frontiers in Microbiology, Review editor, 2022-;

Horticultural Plant Journal, 青年编委，2025.6-2027.5;

Crop Health, 青年编委，2025.4-2027.3

联系方式

邮  箱

wuguanwei@nbu.edu.cn